Place of Origin:
China
Brand Name:
Rps-sonic
Certification:
CE
Model Number:
RPS-SONO20
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Description
The ultrasonic cell pulverizer is based on the cavitation effect of ultrasonic waves in the liquid. The transducer generates high-strength shearing force in the liquid at the top of the tool head through the horn through the electric energy, forming high-frequency alternating water pressure and expanding the cavity , The explosion crushes the cells. It can be used to break animal and plant tissues, cells, bacteria, and spores, and can be used to emulsify, separate, disperse, homogenize, extract, degas, clean and accelerate chemical reactions, etc. Ultrasonic cell pulverizers are widely used in teaching, scientific research, and production in the fields of biochemistry, microbiology, medicinal chemistry, surface chemistry, physics, zoology, agronomy, medicine, and pharmacy.
Principle
Ultrasound is an elastic mechanical wave in a material medium. It is a form of fluctuation, so it can be used to detect the physiological and pathological information of the human body, as well as diagnostic ultrasound. At the same time, it is also a form of energy. When a certain dose of ultrasound is transmitted in the organism, the interaction between them can cause the function and structure of the organism to change, that is, the biological effect of ultrasound.
Ultrasonic cell crusher mainly has thermal effect, cavitation effect and mechanical effect on cells.
The thermal effect is that when the ultrasound propagates in the medium, the frictional force hinders the molecular vibration caused by the ultrasound, which converts part of the energy into local hyperthermia (42-43℃), because the critical lethal temperature of normal tissue is 45.7℃, while that of tumor tissue Normal tissues are highly sensitive, so the metabolism of tumor cells is impaired at this temperature, and DNA, RNA, and protein synthesis are affected, thereby killing cancer cells while normal tissues are not affected.
Cavitation effect is the formation of vacuoles in the organism under ultrasonic irradiation, and mechanical shearing pressure and turbulence are generated with the vibration of the vacuoles and their violent implosion, causing tumor hemorrhage, tissue collapse and necrosis. In addition, instantaneous high temperature (about 5000°C) and high pressure (up to 500×104Pa) are generated when the cavitation bubble bursts, which can thermally dissociate water vapor to produce ·OH radicals and ·H atoms, which are composed of ·OH radicals and ·H Redox reactions caused by atoms can lead to polymer degradation, enzyme inactivation, lipid peroxidation and cell killing.
The mechanical effect is the primary effect of ultrasound. The alternating compression and expansion of the medium particles during the propagation of ultrasound constitutes a pressure change, which causes damage to the cell structure. The strength of the killing effect is closely related to the frequency and intensity of ultrasound.
Function
Ultrasonic cell pulverizer can be used for scientific research in medicine. The research in medicine is mainly the extensive use of the function of crushing. This aspect has extremely high technical requirements.
Ultrasonic cell crusher can be used to crush animal, plant cells, bacteria, dental spores or tissues. Disperse rare earth and various inorganic mineral powders.
Ultrasonic cell crusher is an ideal device to accelerate the reaction speed of chemistry, biology and physics and accelerate the degassing of liquids.
Ultrasonic cell pulverizer can prepare latex with a size of nearly one hundredth of a micron; homogenize the "immiscible" mixture; polymerize some substances and precipitate others.
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